Endocrine Abstracts

Introduction: The incidence of adrenal incidentalomas is 5% among patients undergoing radiological imaging. Differential diagnosis is extremely important, as it determines the tactics of both therapeutic treatment and surgical intervention. Currently, algorithms for the differential diagnosis of adrenal masses have been developed and are widely used. Nevertheless, the compliance with strictly regulated diagnostic protocols does not always allow to make an accurate diagnosis.</...

Introduction: Cushing’s syndrome describes symptoms associated with prolonged exposure to inappropriately high levels of cortisol. It may be increased as a result of high ACTH production in the pituitary gland or from tumours outside pituitary–adrenal system.Case report: Patient 34 years old was hospitalised with complaints of muscle weakness, shooting-pain in thoracic, lumbar spine, decreased height, amenorrhea, arterial hypertension and chang...

Introduction: Lipohypertrophy (LH) is a chronic complication of diabetes mellitus that could develop in any age, any injection site, and be any size. At present time, new method, as ultrasonography of subcutaneous fat, of LH diagnostics were appeared.Design: The aim of this study has been to estimate efficiency of insulinotherapy in diabetic patients after LH was diagnosed by ultrasonography. This study was done on 50 diabetic patients (31 females and 19...

Introduction: Lipohypertrophy (LH) is a chronic complication of diabetes mellitus that caused by frequent subcutaneous injections of insulin. Nowadays, on the basis of results of ultrasonography of subcutaneous fat prevalence of LH in diabetic patients is still high.Design: The aim has been to develop prevention of insulin induced LH in diabetic patients. This study was done on 140 diabetic patients who had been under the treatment with insulin a mean 8 ...

Background: Adrenal insufficiency (AI) in pregnant women is difficult to manage because of similarity between clinics of decompensation of AI and gestational toxicosis. Objective difficulty is absence of clinical guidelines of management of pregnant patients with AI. We present a clinical case where the management of pregnant patient was not careful, which led to overdose and iatrogenic hypercortisolism.Clinical case: Pregnant woman, 29years old, asked s...

Background: Pheochromocytoma (Ph) is the tumor that is fatal if do not suspect and treat it on time. It is supposed that size of tumor is correlated with its synthetic activity. Here we present a clinical case of giant Ph with low synthetic activity that could have been recognized as adrenal cancer, which, in turn, may have led to wrong treatment.Clinical case: Young woman, 28 years old, presented with the adrenal incidentaloma. She had not any complaint...

Introduction: Lipohypertrophy (LH) is a chronic complication of diabetes mellitus that caused by frequent subcutaneous injections of insulin. Nowadays, LH were modified due to good quality modern insulin and expansion their concentration. As a result, some difficulties of diagnosis were appeared.Design: The aim of this study has been to develop the estimation risk model of insulin induced LH in diabetic patients. This study was done on 140 diabetic patie...

Background: Schwannoma (Sch) is a rare peripheral nerve sheath tumor comprised entirely of neoplastic Schwann cells. Adrenal Sch are extremely rare. Most adrenal Sch are incidental, and patients with Sch may not have any complaints. Here we present the clinical case of giant adrenal Sch, which caused hematuria and had indiscriminating organ origin on MRI.Clinical case: Woman, 58 y.o., was consulted by urologist because of painless macrohematuria. Abdomen...

Introduction: Lipohypertrophy (LH) is a chronic complication of diabetes mellitus that caused by frequent s.c. injections of insulin. Nowadays, LH were modified due to good quality modern insulin and expansion their concentration. As a result, some difficulties of diagnosis were appeared.Design: The aim of this study has been to compare the frequency of insulin induced LH in diabetic patients revealed by ultrasonography of subcutaneous fat with those fou...

Introduction: Amyloid goitre is a rare cause of thyroid enlargement, especially as a reason of fast growth. Here we present unusual case of idiopathic AA-amyloidosis as a cause of rapidly growing goitre.Clinical case: Patient 36-year-old presented with complaints of shortness of breath and deglutitive problems during 2 months. His medical history was notable for nephrotic syndrome due to AA-amyloid nephropathy and chronic hepatitis C that were diagnosed ...